Fatigue is a state of reduced physiological performance which impacts on our ability to perform tasks. More than 90% of anaesthesiologists experience work-related fatigue. Over 70% of anaesthesiologists report that work-related fatigue negatively impacts physical and mental health, emotional well-being. Fatigue can pose specific risks for a poorer performance of the anaesthesiologists but also for a worse outcome for the patient. In this webinar, our experts, Nancy Redfern (UK), Igor Abramovich (DE), and Andrea Cortegiani (IT), moderated by Ioana Grigoras (RO), will provide an overview of healthcare professionals’ well-being and its impact on patient safety and discuss strategies to mitigate fatigue.